Endocrine Abstracts

Introduction: During adrenal insufficiency (AI), glucocorticoid treatment is supposed to be neutral on the metabolic parameters of patients. However, recent data from the literature report that this corticosteroid replacement therapy increases the metabolic risk. The aim of our work was to determine the metabolic and cardiovascular impact of hydrocortisone (HC) replacement therapy during peripheral AI.Patients and methods: This was a descriptive and anal...

Introduction: Hydrocortisone (HC) is the most widely used replacement molecule in the treatment of adrenal insufficiency (AI). This substitution treatment is far from ideal especially as it is impossible to reproduce the nycthemeral cycle of cortisol with its current galenic form which has a short half-life. The aim of our work was to determine the impact of HC treatment of peripheral AI on the long-term quality of life and sleep.Patients and methods: Th...

Introduction: The treatment of adrenal insufficiency (AI) is based on long-term glucocorticoid substitution. Hydrocortisone (HC) is the most commonly used substitution molecule. The aim of our work was to determine the long-term bone impact of patients with peripheral AI.Patients and methods: This is a descriptive and analytical study involving 77 patients with peripheral IS (66 women and 11 men), all treated with HC. For each patient, we determined the ...

Introduction: A brown tumor is a rare osteolytic non-neoplastic lesion, due to an anomaly of bone metabolism, occuring in primary, secondary or tertiary hyperparathyroidism.This is a case about a brown tumor with multiple localizations seen in primary hyperparathyroidism.Observation: A 42 year old patient,with a history of Behçet disease diagnosed at the age of 38, is hospitalized in our department for the management of a fort...

Introduction: Pheochromocytomas are rare neuroendocrine tumors arising from chromaffincells of the adrenal gland or extra-adrenal paragangliomas. These tumors cause a hypersecretion of catecholamines, resulting in high blood pressure (HBP) and eventual cardiovascular complications. The point of this study is to go through the different clinical aspects of high blood pressure related to pheochromocytomas.Methods: This is a retrospective study about 8 pati...

Introduction: PCOS is the most common endocrinopathy in adolescents and young women. Insulin–resistance and hyperinsulinism are its primary mechanisms, which explains the frequency of its association with type 2 diabetes. But not many studies have been interested in the association between PCOS and type 1 diabetes.Patients and Methods: Two type 1 diabetes patients have been included in this study, aged respectively 17 and 16. The first patient had ...